TRPC1 (722-733) Goat Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivity	Human, Bovine, Canine, Chicken, Equine, Monkey, Mouse, Porcine, Rabbit, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from internal region of human TRPC1
Specificity	This antibody detects TRPC1 / TRP1 (Internal).
Formulation	Tris saline, pH 7.3 containing 0.02% sodium azide as preservative and 0.5% BSA as stabilizer State: Aff - Purified State: Liquid purfied Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	transient receptor potential cation channel subfamily C member 1
Database Link	Entrez Gene 22063 MouseEntrez Gene 89821 RatEntrez Gene 7220 Human UniProt ID P48995
Background	Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.
Synonyms	Transient receptor protein 1, TRP-1
Reference Data
Protein Families	Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane
Protein Pathways	Calcium signaling pathway, Huntington's disease, Parkinson's disease

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