KCNN4 (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	At 0.5-1μg/ml with the appropriate system to detect KCNN4 in cells and tissues.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a sequence mapping at the C-terminal of human KCNN4
Specificity	This antibody detects KCNN4 at N-term. No cross reactivity with other proteins.
Formulation	5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 State: Aff - Purified State: Lyophilized Ig fraction
Reconstitution Method	0.2ml of distilled water will yield a concentration of 500μg/ml.
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	potassium calcium-activated channel subfamily N member 4
Database Link	Entrez Gene 16534 MouseEntrez Gene 65206 RatEntrez Gene 3783 Human UniProt ID O15554
Background	Intermediate conductance calcium-activated potassium channel protein 1 (KCNN4,Kca3.1) is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. KCNN4 may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily.
Synonyms	KCNN4, IK1, IKCA1, KCA4, SK4, KCa3.1, Putative Gardos channel
Reference Data
Protein Families	Druggable Genome, Ion Channels: Potassium, Transmembrane

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