Apoptosis inhibitor 5 (API5) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot: At 1-2μg/ml with the appropriate system to detect API5 in cells and tissues. Immunohistochemistry on paraffin sections: At 0.5-1μg/ml to detect API5 in formalin fixed and paraffin embedded tissues. Boiling the sections is required.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a sequence at the C-terminal of human API5
Specificity	This antibody detects API5 / MIG8 at C-term.
Formulation	5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 State: Aff - Purified State: Lyophilized Ig fraction
Reconstitution Method	0.2ml of distilled water will yield a concentration of 500μg/ml.
Purification	Affinity-chromatography using epitope-specific immunogen
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	apoptosis inhibitor 5
Database Link	Entrez Gene 11800 MouseEntrez Gene 362170 RatEntrez Gene 8539 Human UniProt ID Q9BZZ5
Background	Many growth factors and cytokines act as cellular survival factors by preventing programmed cell death (apoptosis). Apoptosis inhibitor 5 (API5) is an antiapoptotic factor which may have a role in protein assembly. It is a critical determinant of E2F1-induced apoptosis, acting downstream of E2F to suppress E2F-dependent apoptosis without generally blocking E2F-dependent transcription.
Synonyms	Protein XAGL, FIF, AAC-11
Reference Data
Protein Families	Druggable Genome

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