CD40 (N-term) Rabbit Polyclonal Antibody

CAT#: AP23319PU-N

CD40 (N-term) rabbit polyclonal antibody, Aff - Purified



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CNY 5,599.00


货期*
5周

规格
    • 100 ug

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Specifications

Product Data
Applications WB
Recommend Dilution Westernm blot: 1-2μg/ml with the appropriate system to detect CD40 in cells and tissues.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen A synthetic peptide corresponding to a sequence at the N-terminal of mouse CD40
Specificity This antibody detects CD40 (N-term).
Formulation 50% glycerol, 0.9mg NaCl, 0.2mg Na2HPO4
State: Aff - Purified
State: Lyophilized Ig fraction
Reconstitution Method 1.2% sodium acetate or neutral PBS. If 0.5ml of PBS is used, the antibody concentration will be 100μg/ml.
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Condition Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name CD40 molecule
Background CD40 is a cell surface receptor that is expressed on the surface of all mature B cells and also expressed on monocytes, dendritic cells, and thymic epithelium .CD40 is a member of the tumor necrosis factor (TNF) receptor superfamily and is the receptor for CD40 ligand. CD40 ligand (CD40L,CD154, gp39, and TRAM) belongs to the TNF gene family and is expressed more widely than CD40 predominantly on activated CD4+ T cells. Activation of CD40 has also been shown to inhibit the growth of certain B cell lymphomas and to induce the death of transformed cells of mesenchymal or epithelial origin.
Synonyms TNFRSF5, CDw40, Bp50
Reference Data
Protein Families Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules (CAMs), Cytokine-cytokine receptor interaction, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Viral myocarditis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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