IFITM1 (N-term) Rabbit Polyclonal Antibody

CAT#: AP23332PU-N

IFITM1 (N-term) rabbit polyclonal antibody, Aff - Purified



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CNY 5,599.00


货期*
5周

规格
    • 100 ug

Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution Western blot: At 1μg/ml with the appropriate system to detect IFITM1 in cells and tissues.
Immunohistochemistryon paraffin sections: At 0.5-1μg/ml to detect IFITM1 in formalin fixed and paraffin embedded tissues.
Immunohistochemistry on frozen sections.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a sequence at the N-terminal of human IFITM1
Specificity This antibody detects CD225 / IFITM1 (N-term).
Formulation 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
State: Aff - Purified
State: Lyophilized Ig fraction
Reconstitution Method 0.2ml of distilled water will yield a concentration of 500μg/ml.
Purification Immunogen affinity purified
Conjugation Unconjugated
Storage Condition Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name interferon induced transmembrane protein 1
Background Interferon-induced Transmembrane Protein 1 (IFITM1), also called Interferon-induced Protein 17 (IFI17). IFITM1 activity is required for primordial germ cells (PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins (Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17-kDa proteins to inhibit cell growth.
Synonyms Leu-13 antigen, IFI17
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways B cell receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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