NTE (PNPLA6) (1323-1348) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Western blot 1 μg/ml. Immunohistochemistry on paraffin sections 1-2 μg/ml. Digestion immunohistochemistry on frozen sections: 1-2 µg/ml.
Reactivity	Zebrafish
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a sequence at the C-terminal of fish PNPLA6 (1323-1348 amino acid)
Specificity	This antibody detects NTE at aa 1323-1348. No cross reactivity with other proteins.
Formulation	5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3 State: Aff - Purified State: Lyophilized Ig fraction
Reconstitution Method	0.2ml of distilled water will yield a concentration of 500μg/ml.
Purification	Immunogen affinity purified
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	patatin like phospholipase domain containing 6
Database Link	Entrez Gene 10908 Human UniProt ID Q8IY17
Background	Patatin-like phospholipase domain containing 6 (PNPLA6), also known as Neuropathy target esterase (NTE), is a human gene. Neuropathy target esterase (NTE) is involved in neural development and is the target for neurodegeneration induced by selected organophosphorus pesticides and chemical warfare agents. The genetic or chemical reduction of Nte activity results in a neurological phenotype of hyperactivity in mammals and indicate that EOPF toxicity occurs directly through inhibition of Nte without the requirement for Nte gain of function or aging.
Synonyms	PNPLA6
Reference Data
Protein Families	Transmembrane

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