SH3 containing Grb 2 like 1 protein (SH3GL1) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	Peptide ELISA: Detection Limit: 1/32000. Western blot: 0.3-1 µg/ml. Approx 48kDa band observed in lysates of cell line K562 (calculated MW of 41.5kDa according to NP_003016.1. Immunohistochemistry on Paraffin Sections: Human Small Intestine. 5 µg/ml.
Reactivity	Bovine, Canine, Human
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence from the internal region of the protein sequence according to NP_003016.1.
Specificity	Recognizes Endophilin-A2
Formulation	Tris saline, pH 7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer. State: Aff - Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	SH3 domain containing GRB2 like 1, endophilin A2
Database Link	Entrez Gene 6455 Human UniProt ID Q99961
Background	This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms	Endophilin-2, SH3GL1, CNSA1, SH3D2B
Reference Data

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