Ephrin B2 (EFNB2) pTyr316 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1:500~1:1000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide sequence around phosphorylation site of tyrosine 316 (P-V-Y(p)-I-V) derived from Human Ephrin-B2
Specificity	This antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 316.
Formulation	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity-chromatography using epitope-specific peptide
Conjugation	Unconjugated
Storage Condition	Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Gene Name	ephrin B2
Database Link	Entrez Gene 13642 MouseEntrez Gene 1948 Human UniProt ID P52799
Background	This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene.
Synonyms	EFNB2, EPLG5, HTKL, LERK5, HTK-L, LERK-5, HTK ligand
Note	Molecular weight: 37 kDa
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Axon guidance

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