Ephrin B2 (EFNB2) pTyr330 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1:500~1:1000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide sequence around phosphorylation site of tyrosine 330 derived from Human Ephrin-B2
Specificity	This antibody detects endogenous levels of Ephrin-B2 only when phosphorylated at tyrosine 330.
Formulation	Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Affinity-chromatography using epitope-specific peptide
Conjugation	Unconjugated
Storage Condition	Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Gene Name	ephrin B2
Database Link	Entrez Gene 13642 MouseEntrez Gene 1948 Human UniProt ID P52799
Background	Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
Synonyms	EFNB2, EPLG5, HTKL, LERK5, HTK-L, LERK-5, HTK ligand
Note	Molecular weight: 37 kDa
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Axon guidance

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