CD95 (FAS) (323-327) Rabbit Polyclonal Antibody

CAT#: AP26059PU-S

CD95 (FAS) (323-327) rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul



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CNY 1,400.00


货期*
2周

规格
    • 50 ul

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Specifications

Product Data
Applications WB
Recommend Dilution Western blot: 1:1000.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around aa.323~327 derived from human Fas .
Specificity This antibody detects endogenous level of total Fas protein.
Formulation Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity-chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Condition Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Gene Name Fas cell surface death receptor
Background Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).
Synonyms FASLG receptor, Apo-1 antigen, APT1, FAS1, TNFRSF6
Note Molecular weight: 40-50 kDa
Reference Data
Protein Families Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways Allograft rejection, Alzheimer's disease, Apoptosis, Autoimmune thyroid disease, Cytokine-cytokine receptor interaction, Graft-versus-host disease, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, p53 signaling pathway, Pathways in cancer, Type I diabetes mellitus
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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