Caspase 9 (CASP9) (301-305) Rabbit Polyclonal Antibody

CAT#: AP26062PU-S

Caspase 9 (CASP9) (301-305) rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul



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CNY 1,400.00


货期*
2周

规格
    • 50 ul

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Specifications

Product Data
Applications WB
Recommend Dilution Western blot: 1:1000.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around aa.301~305 derived from Caspase 9
Specificity This antibody detects endogenous level of total Caspase 9 protein.
Formulation Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity-chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Condition Store (in aliquots) at -20 °C. Avoid repeated freezing and thawing.
Gene Name caspase 9
Background Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Synonyms CASP-9, CASP9, MCH6, ICE-LAP6, APAF-3, APAF3
Note Molecular weight: 47/37/35 kDa
Reference Data
Protein Families Druggable Genome, Protease, Stem cell - Pluripotency
Protein Pathways Alzheimer's disease, Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Endometrial cancer, Huntington's disease, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Parkinson's disease, Pathways in cancer, Prostate cancer, Small cell lung cancer, VEGF signaling pathway, Viral myocarditis
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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