NF-kB p65 (RELA) pSer468 Rabbit Polyclonal Antibody
CAT#: AP26421AF-N
NF-kB p65 (RELA) pSer468 rabbit polyclonal antibody, Azide Free
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CNY 5,621.00
货期*
4周
规格
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Specifications
Product Data | |
Applications | ELISA |
Recommend Dilution | ELISA: The antibody (approx. 1:50,000 -1:120,000 diluted) can detect the serine 468 phosphorylated NF-κB p65 peptide coated on ELISA plate at 100ng/well. |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic peptide derived from Serine 468 phosphorylated NF-κB p65, conjugated with KLH |
Specificity | This antibody is reactive to the synthetic NF-κB -p65 peptide (FTDLASpVDNSE) with Mouse, Human and other species with consensus serine 468 phosphorylated NF-κB -p65 peptide. |
Formulation | State: Azide Free State: Lyophilized Ig fraction |
Purification | Protein G affinity |
Conjugation | Unconjugated |
Storage Condition | Store lyophilized at 2-8°C for 6 month or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Gene Name | RELA proto-oncogene, NF-kB subunit |
Database Link | |
Background | NF-κB (nuclear factor kappa-light-chainenhancer of activated B cells) is a transcription factor that controls the transcription of many genes that are associated with immuno-response, antiapoptosis, neuroplasticity and memory. There are five NF-κB proteins in mammals: RelA(NF-κB-p65), RelB, c-Rel, NF-κB (NF-κB-p105), and NF-κB2 (NF- κB-p100). They form a variety of homodimers and heterodimers, each of which activates its own distinctive set of genes. P65 has been shown to be involved with DNA binding. The phosphorylation of p65 at Ser468 is inducible by TNF. The phosphorylation mediates p65 ubiquitination and the termination of related gene expression. |
Synonyms | NF kappa B p65, NFkB p65, Transcription factor p65, Rel A, NFKB3 |
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