alpha smooth muscle Actin (ACTA2) (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 1/100.
Reactivity	Bovine, Chicken, Human, Monkey, Mouse, Rabbit, Rat, Baboon
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide from N-terminus of Human alpha smooth muscle isoform of Actin
Specificity	This antibody stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also stained. It reacts with tumors arising from smooth muscles and myoepithelial cells. Actin from fibroblasts (beta- and gamma-cytoplasmic), striated muscle (alpha-sarcomeric), and myocardium (alpha-myocardial) are not labeled.
Formulation	10 mM PBS, pH 7.4 State: Purified State: Liquid purified Ig fraction Stabilizer: BSA Preservative: 0.09% Sodium Azide
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	actin, alpha 2, smooth muscle, aorta
Database Link	Entrez Gene 11475 MouseEntrez Gene 81633 RatEntrez Gene 100427024 MonkeyEntrez Gene 59 Human UniProt ID P62736
Background	Actin alpha 2, the human aortic smooth muscle actin gene, is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.
Synonyms	ACTSA, ACTVS, Alpha-actin-2
Reference Data
Protein Pathways	Vascular smooth muscle contraction

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