Dysferlin (DYSF) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	Immunohistochemistry on Paraffin Sections: 1/50. Western Blot: 1 µg/ml.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to C-terminal of human Dysferlin
Specificity	This antibody reacts to Dysferlin, Limb Girdle Muscular Dystrophy 2b (AUTOSOMAL RECESSIVE) (DYSF).
Formulation	10 mM PBS, pH 7.4 containing BSA as stabilizer and 0,09% sodium azide as preservative State: Purified State: Liquid purfied Ig fraction
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C. DO NOT FREEZE!
Gene Name	dysferlin
Database Link	Entrez Gene 8291 Human UniProt ID O75923
Background	Dysferlin is the protein product of the 2p13 gene that is defective in patients with Limb-Girdle Muscular Dystrophy type 2B (LGMD2B) and Miyoshi Myopathy (MM). Dysferlin is normally localized to the muscle plasma membrane. In patients with LGMD2B and MM, immunoreactivity to dysferlin is severely reduced or lost, depending on the type of mutation. This antibody is used for the characterization of LGMD2B and MM.
Synonyms	Fer-1-like protein 1, DYSF, FER1L1
Reference Data
Protein Families	Transmembrane

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.