Prostatic Acid Phosphatase (ACPP) (269-282) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	Peptide ELISA: Detection Limit: 1/32000. Western Blot: 0.01-0.03 µg/ml. Approx 50kDa band observed in Human Prostate lysates.  Immunohistochemistry on Paraffin Sections: 3-5 μg/ml. In paraffin embedded Human Prostate shows reticulate cytoplasm staining, more intens towards the lumen of the gland.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence from the internal region of the protein sequence according to NP_001127666.1, NP_001090.2.
Specificity	This antibody is expected to recognize both reported isoforms (NP_001127666.1; NP_001090.2).
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	acid phosphatase, prostate
Database Link	Entrez Gene 55 Human UniProt ID P15309
Background	Prostatic acid phosphatase is one of the two antigenic markers of prostatic carcinoma, the other being prostate specific antigen. It belongs to the kallikrein family of serine proteases and is suggested to act as a hydrolase to split phospharyl choline in semen and as a transferase.
Synonyms	Prostate acid phosphatase, PAP, ACP3, PSAP
Note	Calculated Molecular Weight: 48.3kDa (NP_001127666.1).
Reference Data
Protein Families	Druggable Genome, Phosphatase, Transmembrane
Protein Pathways	Riboflavin metabolism

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