Alk Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: Detection Limit: 1/32000. Western Blot: 0.03-0.1 µg/ml. Approx 150kDa band observed in Rat Brain lysates (calculated MW of 175kDa according to Rat NP_001162572.1).
Reactivity	Mouse, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence from the internal region of the protein sequence according to NP_031465.2.
Specificity	This antibody recognizes CD246/ALk
Formulation	Tris saline, pH~7.3 containing 0.02% Sodium Azide as preservative and 0.5% BSA as stabilizer State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	anaplastic lymphoma kinase
Database Link	Entrez Gene 11682 Mouse UniProt ID P97793
Background	LTK, ALK and Ros have been identified as receptor tyrosine kinases having sequence similarity to the insulin receptor subfamily of kinases. LTK, leukocyte tyrosine kinase, is expressed in murine B-lymphocyte precursors and has also been found in forebrain neurons. ALK, anaplastic lymphoma kinase, is normally highly expressed specifically in the nervous system. A truncated form containing the catalytic domian of ALK is expressed as the result of a translocation occuring in many non-Hodgkin’s lymphomas. The c-Ros gene was originally identified in mutant form as an oncogene. Ros is normally expressed in a small number of epithelial cell types and may play a role in epithelial development.
Synonyms	ALK tyrosine kinase receptor
Reference Data

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