Desmoglein 1 (DSG1) (841-855) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC
Recommend Dilution	ELISA: 1/32000. Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide from an internal region of human DSG1 (NP_001933.2)
Specificity	This antibody reacts to the internal region of DSG1.
Formulation	Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	desmoglein 1
Database Link	Entrez Gene 1828 Human UniProt ID Q02413
Background	Desmosomes are a type of intercellular junction between epithelial, myocardial, and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein isoforms have been identified: DSG1, DSG2 and DSG3; all members of the cadherin cell adhesion molecule family. DSG1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.
Synonyms	Desmosomal glycoprotein 1, Pemphigus foliaceus antigen, DSG1, CDHF4, DG1, DGI
Reference Data
Protein Families	Druggable Genome

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