Insulin (INS) Sheep Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	ELISA.
Reactivity	Human
Host	Sheep
Clonality	Polyclonal
Immunogen	C-Peptide conjugate EAEDLQVGQVKKKC- KLH
Specificity	Recognizes Human C-Peptide.
Formulation	PBS, pH 7.4 containing 0.09% Sodium Azide as preservative State: Aff - Purified State: Lyophilized purified Ig fraction
Reconstitution Method	Restore in aqua bidest to 1.0 mg/ml
Purification	Affinity Chromatography against target peptide and cross adsorbed on an affinity column of immobilised Mouse immunoglobulin
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C and reconstituted (in aliquots) at -20°C. Avoid repeated freezing and thawing.
Gene Name	insulin
Database Link	Entrez Gene 3630 Human UniProt ID P01308
Background	C-Peptide is part of the molecule of Proinsulin, that consists of three parts: C Peptide and two long strands of amino acids (called the alpha and beta chains) that later become linked together to form the insulin molecule. From every molecule of proinsulin, one molecule of insulin plus one molecule of C Peptide are produced C Peptide is released into the bloodstream in equal amounts to insulin. A test of C Peptide levels will show how much insulin the body is making.
Synonyms	INS
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein
Protein Pathways	Insulin signaling pathway, Maturity onset diabetes of the young, mTOR signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Regulation of autophagy, Type I diabetes mellitus, Type II diabetes mellitus

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