CDw75 (ST6GAL1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA: 1/40000. Immunohistochemistry on Paraffin Sections: 1/200. Western Blot: 1/500 - 1/1000.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to the Internal region of Human ST6GAL1.
Specificity	This antibody detects endogenous levels of total ST6GAL1 protein.
Formulation	PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol State: Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody (in aliquots) at -20°C or lower. Avoid freeze-thaw cycles.
Gene Name	ST6 beta-galactoside alpha-2,6-sialyltransferase 1
Database Link	Entrez Gene 20440 MouseEntrez Gene 25197 RatEntrez Gene 6480 Human UniProt ID P15907
Background	The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein, which is normally found in the Golgi but which can be proteolytically processed to a soluble form, is involved in the generation of the cell-surface carbohydrate determinants and differentiation antigens HB-6, CDw75, and CD76. This protein is a member of glycosyltransferase family 29. Three transcript variants encoding two different isoforms have been found for this gene.
Synonyms	SIAT1, B-Cell marker
Reference Data
Protein Families	Secreted Protein
Protein Pathways	Metabolic pathways, N-Glycan biosynthesis

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