DAPP1 (C-term) Goat Polyclonal Antibody
CAT#: AP31920PU-N
DAPP1 (C-term) goat polyclonal antibody, Aff - Purified
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CNY 5,371.00
货期*
4周
规格
Specifications
Product Data | |
Applications | ELISA, WB |
Recommend Dilution | Peptide ELISA: 1/4000 (Detection limit). |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Immunogen | Peptide with sequence SALCISPEEKTDHK, from the C Terminus of the protein sequence according to AAF14578.1. |
Specificity | This antibody recognizes DAPP1 |
Formulation | Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Predicted Protein Size | 32.0 kDa (AAF14578.1). |
Gene Name | dual adaptor of phosphotyrosine and 3-phosphoinositides 1 |
Database Link | |
Background | B cell adapter molecule (BAM32) is also designated a dual adapter for phosphotyrosine and 3-phosphotyrosine, and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC γ2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation. BAM32, which contains one PH domain and one SH2 domain, is primarily expressed in placenta and lung tissues, but can also be detected in heart, liver, pancreas and brain. |
Synonyms | BAM32, HSPC066, DKFZp667E0716, hDAPP1 |
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