DAPP1 (C-term) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: 1/4000 (Detection limit). Western Blot: 0.5-1 µg/ml. Approx 30kDa band observed in Human Kidney lysates.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence SALCISPEEKTDHK, from the C Terminus of the protein sequence according to AAF14578.1.
Specificity	This antibody recognizes DAPP1
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	32.0 kDa (AAF14578.1).
Gene Name	dual adaptor of phosphotyrosine and 3-phosphoinositides 1
Database Link	Entrez Gene 27071 Human UniProt ID Q9UN19
Background	B cell adapter molecule (BAM32) is also designated a dual adapter for phosphotyrosine and 3-phosphotyrosine, and 3-phosphoinositide (DAPP1) or B lymphocyte adapter protein. BAM32 is a B cell-associated adapter that is crucial for B cell antigen receptor signaling regulation. BAM32 interacts with Ptdlns and PLC γ2 and, upon B cell activation, the protein is phosphorylated on tyrosine residues. It is a mainly cytoplasmic protein that can translocate to the cell membrane after cell stimulation. BAM32, which contains one PH domain and one SH2 domain, is primarily expressed in placenta and lung tissues, but can also be detected in heart, liver, pancreas and brain.
Synonyms	BAM32, HSPC066, DKFZp667E0716, hDAPP1
Reference Data

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