JNK2 (MAPK9) (217-230) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, WB
Recommend Dilution	Peptide ELISA: 1/16000 (Detection limit). Western Blot: 0.03-0.1 µg/ml. Detects a band of ~48kDa band observed in lysates of cell line HeLa.
Reactivity	Canine, Human, Mouse, Rat
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence from the internal region of the protein sequence according to NP_620707.1; NP_002743.3; NP_001128516.1.
Specificity	This antibody is expected to recognize isoforms alpha 1, alpha 2. and gamma (NP_620707.1, NP_002743.3, NP_001128516.1).
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	48.1 kDa (NP_002743.3).
Gene Name	mitogen-activated protein kinase 9
Database Link	Entrez Gene 5601 Human UniProt ID P45984
Background	JNK2, a MAPK type protein kinase, regulates cell apoptosis, differentiation and growth in response to growth factors, inflammatory cytokines and cellular stress. JNK2 is phosphorylated by by MKK4/MAP2K4 and MKK7/MAP2K7. Activated JNK2 translocates to the nucleus where it phosphorylates transcription factors, including c-Jun, ATF2, ELK1, Jun-D and NFAT4. At least four distinct isoforms, resulting from alternatively spliced transcript variants, have been reported - three different isoforms comprised of 382 amino acids and one comprised of 424 amino acids.
Synonyms	JNK-55, PRKM9, MAP kinase 9
Reference Data

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