CCR1 (7-24) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA: 1/100000. Immunocytochemistry: 1/400. Immunohistochemistry on Paraffin Sections: 5 µg/ml. Western Blot: 1/1000.
Reactivity	Human
Host	Goat
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to amino acids 7-24 of the N-terminal extracellular domain of Human CCR1
Specificity	This antibody recognizes CCR1 (N-term).
Formulation	10 mM KHPO4, 140 mM NaCl with 1 mg/ml BSA and 0.09% sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Immunoaffinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	C-C motif chemokine receptor 1
Database Link	Entrez Gene 1230 Human UniProt ID P32246
Background	CCR1, a Chemokine Receptor, affects stem cell proliferation and mediates systemic inflammatory responses. This receptor is stimulated by the beta chemokines RANTES, MCP-1, and MIP-1 alpha. Disruption of CCR1 enhances protection from pulmonary inflammation and reduces the development of respiratory distress syndrome in rat.
Synonyms	C-C chemokine receptor type 1, C-C CKR-1, CC-CKR-1, CCR-1, CMKBR1, CMKR1, SCYAR1, HM145, LD78 receptor
Note	Peptide sequence is <50 % identical to other chemokine receptors in this region and has no cross-reactivity to mouse CCR.
Reference Data

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