Calpain 3 (CAPN3) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IHC, WB
Recommend Dilution	ELISA: 1/1000. Western blot: 1/50 - 1/100. Immunohistochemistry on paraffin sections: 1/50 - 1/100. Flow cytometric: 1/10 - 1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 610~640 amino acids from the C-terminal region of human CAPN
Specificity	This antibody reacts to CAPN3.
Formulation	PBS State: Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	Saturated Ammonium Sulfate (SAS) precipitation
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	94254 Da
Gene Name	calpain 3
Database Link	Entrez Gene 825 Human UniProt ID P20807
Background	Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A.
Synonyms	Calpain L3, Calpain p94, New calpain 1, CAPN3, CANP3, CANPL3, NCL1
Reference Data
Protein Families	Druggable Genome, Protease

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