CENPH (Center) Rabbit Polyclonal Antibody
CAT#: AP50854PU-N
CENPH (Center) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | FC, IHC, WB |
Recommend Dilution | ELISA: 1/1000. Western blot: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100. Flow cytometric: 1/10 - 1/50. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide selected from the Center region of human CENPH |
Specificity | This antibody reacts to CENPH. |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) sodium azide |
Concentration | lot specific |
Purification | Affinity chromatography on Protein A |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Predicted Protein Size | 28481 Da |
Gene Name | centromere protein H |
Database Link | |
Background | Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. |
Synonyms | Centromere protein H, CENPH, ICEN35 |
Reference Data | |
Protein Families | Druggable Genome |
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