CYBA (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500.  Immunofluorescence: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 124-153 amino acids from the C-terminal region of Human Cytochrome b-245 light chain.
Specificity	This antibody recognizes Human Cytochrome b-245 light chain (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	cytochrome b-245 alpha chain
Database Link	Entrez Gene 1535 Human UniProt ID P13498
Background	Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
Synonyms	CYBA, p22-phox, Cytochrome b558 subunit alpha
Note	Molecular Weight: 21013 Da
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Leukocyte transendothelial migration

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