Desmocollin 3 (DSC3) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Peptide ELISA: 1/1,000.  Western Blot: 1/1,000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 822-850 amino acids from the C-terminal region of Human Desmocollin-3.
Specificity	This antibody recognizes Human and Mouse Desmocollin-3 (C-term).
Formulation	PBS with 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	desmocollin 3
Database Link	Entrez Gene 13507 MouseEntrez Gene 1825 Human UniProt ID Q14574
Background	The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.
Synonyms	Desmocollin-4, HT-CP, DSC3, CDHF3, DSC4
Note	Molecular Weight: 99969 Da
Reference Data
Protein Families	Transmembrane

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