FSTL3 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500. Immunohistochemistry on Paraffin Sections: 1/10-1/50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 228-258 amino acids from the C-terminal region of Human FSTL3
Specificity	Recognizes Follistatin-related protein 3 (C-term).
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	27663 Da
Gene Name	follistatin like 3
Database Link	Entrez Gene 10272 Human UniProt ID O95633
Background	FSTL3, follistatin-like 3, is a secreted glycoprotein of the follistatin-module-protein family. FSTL3 is expressed in the placenta and may play a role in regulating the extracellular matrix of the placenta. FSTL3 is a binding protein for activin and BMP2 and thought to regulate activin and myostatin during normal adult metabolic homeostasis. FSTL3 may also contribute to bone formation by inhibiting osteoclast differentiation from hematopoietic precursors. A chromosomal aberration involving FSTL3 is found in a case of B-cell chronic lymphocytic leukemia.
Synonyms	Follistatin-like 3, Follistatin-related gene protein, FLRG, FSTL3
Reference Data
Protein Families	Secreted Protein

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