FUT3 (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1000. Western Blot: 1/100-1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 294~324 amino acids from the C-terminal region of human Fucosyltransferase 3
Specificity	This antibody recognizes Human Fucosyltransferase 3 (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	fucosyltransferase 3 (Lewis blood group)
Database Link	Entrez Gene 2525 Human UniProt ID P21217
Background	FUT3 comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This protein is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities.
Synonyms	FUT3, FT3B, LE, Fucosyltransferase III, Lewis FT, FucT-III
Note	Molecular Weight: 42117 Da
Reference Data
Protein Pathways	Glycosphingolipid biosynthesis - lacto and neolacto series, Metabolic pathways

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