Uroguanylin (GUCA2B) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA:  1/1000.  Western Blot: 1/100-1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 68-97 amino acids from the C-terminal region of human GUCA2B
Specificity	This antibody recognizes Human GUCA2B (C-term).
Formulation	PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Protein A column, followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	guanylate cyclase activator 2B
Database Link	Entrez Gene 2981 Human UniProt ID Q16661
Background	Uroguanylin and guanylin (GUCA2A; MIM 139392), peptide homologs of the bacterial heat-stable enterotoxins (e.g., the E. coli ST toxin; STa), are endogenous activators of the guanylate cyclase-2C receptor (GUCY2C; MIM 601330), which synthesizes cyclic GMP (cGMP), a key component of several intracellular signal transduction pathways.
Synonyms	Guanylate cyclase activator 2B, Guanylate cyclase C-activating peptide 2, GCAP-II, Uroguanylin, UGN
Note	Molecular Weight: 12069 Da
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane

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