L2HGDH (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	This antibody is suitable for Western blotting. The suggested dilution is:  1/100-1/500.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the central region (between 139-167aa) of human L2HGDH/Duranin.
Specificity	This antibody detects L2HGDH/ Duranin.
Formulation	PBS with 0.09% (W/V) Sodium Azide. State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Purified through a protein A column; followed by peptide affinity purification.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	L-2-hydroxyglutarate dehydrogenase
Database Link	Entrez Gene 217666 MouseEntrez Gene 79944 Human UniProt ID Q9H9P8
Background	The L2HGDH  gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.
Synonyms	L2HGDH, C14orf160, hydroxyglutarate dehydrogenase
Note	Molecular Weight: 50359 Da
Reference Data
Protein Pathways	Butanoate metabolism

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