nkx6.1 (NKX6-1) (C-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	Western blot: 1/100-1/500. Enzyme immunoassay: 1/1000.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 284-314aa) of human NKX6-1
Specificity	This antibody recognizes NKX6-1 at C-term.
Formulation	PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction
Concentration	lot specific
Purification	Purified through a Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	NK6 homeobox 1
Database Link	Entrez Gene 18096 MouseEntrez Gene 4825 Human UniProt ID P78426
Background	In the pancreas, NKX6-1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes. [Iype et al., 2004; PubMed 15056733]
Synonyms	NKX6A
Note	Molecular Weight: 37849 Da
Reference Data
Protein Families	Transcription Factors
Protein Pathways	Maturity onset diabetes of the young

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