FISH (SH3PXD2A) (N-term) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1/1,000.  Western blotting: 1/100-1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 221-250 amino acids from the N-terminal region of Human SH3PXD2A
Specificity	Recognizes SH3PXD2A (N-term) .
Formulation	PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% (W/V) Sodium Azide
Concentration	lot specific
Purification	Protein A column followed by peptide Affinity purification
Conjugation	Unconjugated
Gene Name	SH3 and PX domains 2A
Database Link	Entrez Gene 9644 Human UniProt ID Q5TCZ1
Background	SH3PXD2A is required for podosome formation, degradation of the extracellular matrix, and for the invasiveness of some cancer cells. Binds phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 3,4-biphosphate (PtdIns(3,4)P2). In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide.
Synonyms	FISH, KIAA0418, SH3MD1, TKS5
Note	Molecular Weight: 125289 Da
Reference Data

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