SPR (C-term) Rabbit Polyclonal Antibody
CAT#: AP54030PU-N
SPR (C-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,314.00
货期*
5周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | Western blot: 1/100-1/500. Enzyme immunoassay: 1/1000. |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 232-261aa) of human Sepiapterin reductase / SPR. |
Specificity | This antibody recognizes Sepiapterin reductase / SPRat N-term. |
Formulation | PBS with 0.09% (W/V) Sodium azide State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Purified through a Protein A column followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Gene Name | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
Database Link | |
Background | The SPR gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiapterin reductase deficiency. A pseudogene has been identified on chromosome 1. |
Synonyms | SDR38C1, EC 1.1.1.153 |
Note | Molecular Weight: 28048 Da |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Folate biosynthesis, Metabolic pathways |
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