HOX11 (TLX1) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	ELISA: 1:1;000. Western blot: 1:100~500.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 162-191 amino acids from the Central region of human TLX1
Specificity	This antibody detects TLX1 (Center).
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	T-cell leukemia homeobox 1
Database Link	Entrez Gene 21908 MouseEntrez Gene 3195 Human UniProt ID P31314
Background	This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants.
Synonyms	TLX-1, T-cell leukemia homeobox protein 1, HOX11, Hox-11, TCL3, TCL-3
Note	Molecular Weight: 34365 Da
Reference Data

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