CD252 (TNFSF4) (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, WB
Recommend Dilution	ELISA: 1:1;000. Western blot: 1:100~500. Flow cytometry: 1:10~50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human TNFSF4
Specificity	This antibody detects CD252 / TNFSF4 (Center).
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	tumor necrosis factor superfamily member 4
Database Link	Entrez Gene 7292 Human UniProt ID P23510
Background	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
Synonyms	TXGP1, OX40 ligand, OX40L, Glycoprotein Gp34
Note	Molecular Weight: 21050 Da
Reference Data
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Cytokine-cytokine receptor interaction

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