UBF1 (UBTF) (C-term) Rabbit Polyclonal Antibody
CAT#: AP54449PU-N
UBF1 (UBTF) (C-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | ELISA: 1:1;000. Western blot: 1:100~500. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 630-660 amino acids from the C-terminal region of human UBTF |
Specificity | This antibody detects UBTF / UBF (C-term). |
Formulation | PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction |
Concentration | lot specific |
Purification | Protein A column followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing. |
Gene Name | upstream binding transcription factor, RNA polymerase I |
Database Link | |
Background | Upstream binding factor (UBF) is a transcription factor required for expression of the 18S, 5.8S, and 28S ribosomal RNAs, along with SL1 (a complex of TBP (MIM 600075) and multiple TBP-associated factors or 'TAFs'). Two UBF polypeptides, of 94 and 97 kD, exist in the human (Bell et al., 1988 [PubMed 3413483]). UBF is a nucleolar phosphoprotein with both DNA binding and transactivation domains. Sequence-specific DNA binding to the core and upstream control elements of the human rRNA promoter is mediated through several HMG boxes (Jantzen et al., 1990 [PubMed 2330041]). |
Synonyms | Nucleolar transcription factor 1, Upstream-binding factor 1, UBF1, UBF-1, Autoantigen NOR-90 |
Note | Molecular Weight: 89406 Da |
Reference Data | |
Protein Families | Transcription Factors |
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