UROC1 (Center) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	ELISA: 1:1;000. Western blot: 1:100~500. Immunohistochemistry on paraffin sections: 1:10~50.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	KLH conjugated synthetic peptide between 409-437 amino acids from the Central region of human UROC1
Specificity	This antibody detects UROC1 (Center).
Formulation	PBS with 0.09% (W/V) sodium azide State: Aff - Purified State: Liquid Ig fraction
Concentration	lot specific
Purification	Protein A column followed by peptide affinity purification
Conjugation	Unconjugated
Storage Condition	Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Gene Name	urocanate hydratase 1
Database Link	Entrez Gene 131669 Human UniProt ID Q96N76
Background	This gene encodes an enzyme involved in histidine catabolism, metabolizing urocanic acid to formiminoglutamic acid. The gene product is known to protect the skin from ultra violet rays and is contained in human sweat. Deficiency of this gene product in the liver is an apparent cause of mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms	Urocanate hydratase
Note	Molecular Weight: 74831 Da
Reference Data
Protein Pathways	Histidine metabolism, Metabolic pathways

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