CLCNKB Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/200-1/1000. Immunohistochemistry: 1/500-1/5000.
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from C-terminal domain of ClC-Kb protein.
Specificity	Reacts with Mouse 75 kDa Clcnkb protein.
Formulation	State: Serum State: Lyophilized powder Preservative: None
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store the antibody at -20°C. Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	chloride channel, voltage-sensitive Kb
Database Link	Entrez Gene 56365 Mouse UniProt ID Q9WUB6
Background	Chloride channel Kb (CLCNKB) is a member of the CLC family of voltage-gated chloride channels, which comprises at least 9 mammalian chloride channels. Each is believed to have 12 transmembrane domains and intracellular N and C termini. Mutations in CLCNKB result in the autosomal recessive Type III Bartter Syndrome. CLCNKA and CLCNKB are closely related (94% sequence identity), tightly linked (separated by 11 kb of genomic sequence) and are both expressed in mammalian kidney.
Synonyms	Chloride channel protein ClC-Kb, Chloride channel Kb, ClC-K2, ClCK2
Reference Data

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