Dpysl2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IF, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/2000. Immunohistochemistry: 1/500.
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	A 15 residue synthetic peptide derived from C-terminal domain of Human Collapsing-Response Mediator.
Specificity	This antibody reacts with 65 kDa CRMP-2. It do not react with CRMP-1, CRMP-3, CRMP-4 or CRMP-5.
Formulation	State: Serum State: Lyophilized serum Preservative: None
Reconstitution Method	Restore in distilled water.
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	dihydropyrimidinase-like 2
Database Link	Entrez Gene 12934 Mouse UniProt ID O08553
Background	CRMP2 is 62 kDa member of the dehydropyrimidinase family. It is involved in axon formation and outgrowth by transporting to axons, the actin cytoskeleton regulating; Rac1-associated protein 1 (Sra-1)/WASP family verprolin-homologous protein 1 (WAVE1) complex. CRMP2 also regulates axon formation and branching by binding tubulin heterodimers thereby enhancing microtubule polymerisation. Through its interaction with ROKalpha, CRMP2 is also thought to play a role in RhoA-dependent signalling. CRMP2 is associated with mesial temporal lobe epilepsy and schizophrenia.
Synonyms	Dihydropyrimidinase-related protein 2, DRP-2, N2A3
Reference Data

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