CRMP4 (DPYSL3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/2000. Immunohistochemistry: 1/500.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	A 15 residue synthetic peptide derived from C-terminal domain of Human Collapsing-Response Mediator.
Specificity	Reacts with 65 kDa CRMP-4. This antibody does not react with CRMP-1, CRMP-2, CRMP-3 or CRMP-5.
Formulation	0.1M Tris, 0.1M Glycine, 2% Sucrose State: Purified State: Lyophilized purified antibody Preservative: None
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Purification	Affinity Chromatography on Protein A
Conjugation	Unconjugated
Storage Condition	Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month  or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing.
Gene Name	dihydropyrimidinase like 3
Database Link	Entrez Gene 1809 Human UniProt ID Q14195
Background	The collapsin response mediator protein (CRMP) family of five cytosolic phosphoproteins are highly expressed throughout brain development. The functions of CRMPs encompass signal transduction in developmental guidance cues as well as multiple cellular and molecular events involved in apoptosis/proliferation, cell migration, and differentiation. In the adult brain, the expression of CRMPs is dramatically downregulated. However, CRMPs remain expressed in structures that retain their capacity for differentiation and plasticity. The expression of CRMPs is altered in neurodegenerative diseases, and these proteins may have a role in the physiopathology of the adult nervous system.
Synonyms	CRMP-4, DRP3, DRP-3, ULIP, ULIP1, ULIP-1, TUC-4
Reference Data

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