Ybx1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/100-1/1000. Immunohistochemistry: 1/50-1/200.
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from N-terminal domain of Mouse YBOX1 protein
Specificity	Reacts with Mouse 36 kDa protein. This antibody cross reacts with proteins from Human, Rat and other species.
Formulation	State: Serum State: Lyophilized serum Preservative: None
Reconstitution Method	Restore in distilled water.
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store the antibody at -20°C. Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer Avoid repeated freezing and thawing.
Gene Name	Y box protein 1
Database Link	Entrez Gene 22608 Mouse UniProt ID P62960
Background	YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. This protein binds and stabilizes cytoplasmic mRNA and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. It regulates the transcription of numerous genes and promotes separation of DNA strands that contain mismatches or are modified by cisplatin. It has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro), and it may play a role in DNA repair.
Synonyms	NSEP1, YB1, CBF-A, EFI-A
Reference Data

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