PAR4 (PAWR) Rabbit Polyclonal Antibody

CAT#: AP55133PU-N

PAR4 (PAWR) rabbit polyclonal antibody, Purified



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CNY 6,886.00


货期*
8周

规格
    • 100 ug

Product images

Specifications

Product Data
Applications ELISA, IHC, WB
Recommend Dilution

ELISA.
Western Blot: 1/100-1/1000.
Immunohistochemistry: 1/50-1/500.

Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide derived from internal domain of Human Par-4.
Specificity Reacts with Human 36 kDa Par-4 protein.
Formulation 0.1M Tris, 0.1M Glycine and 2% Sucrose
State: Purified
State: Lyophilized purified antibody
Preservative: None
Reconstitution Method Restore in distilled water.
Purification Affinity Chromatography on Protein A
Conjugation Unconjugated
Storage Condition

Prior to reconstitution store the antibody at -20°C.
Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Gene Name pro-apoptotic WT1 regulator
Background Prostate apoptosis response 4 (Par4) is a 38kD protein originally identified as the product of a gene that is upregulated in prostate tumor cells undergoing apoptosis. It is a leucine zipper and death domain containing protein whose levels increase in neurons undergoing apoptosis as a result of trophic factor withdrawal or exposure to oxidative and metabolic insults. Par4 levels are reported to be increased in their lumbar spinal cord specimens further suggesting a role in neuronal degeneration. The tumor suppressor WT1 represses and activates transcription. The loss and/or imbalance of the dual transcriptional activity of WT1 may contribute to Wilms tumor. Par4 is a WT1 interacting protein that also functions as a transcriptional repressor.
Synonyms Par-4
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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