PACAP receptor (ADCYAP1R1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/1000-1/5000. Immunohistochemistry: 1/100-1/1000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from extracellular domain of Human PACAP-R-1 protein
Specificity	This antibody reacts with the53 kDa PACR protein. May cross-reacts with the protein from Mouse, Rat proteins and other species due to sequence homology.
Formulation	0.1M Tris, 0.1M Glycine, 2% Sucrose State: Serum State: Lyophilized Serum
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Prior to reconstitution store at -20°C. Following reconstitution store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	ADCYAP receptor type I
Database Link	Entrez Gene 117 Human UniProt ID P41586
Background	The PACAP receptor type 1, a member of the vasoactive intestinal polypeptide subfamily, binds the hormone pituitary adenylate cyclase activating polypeptide (PACAP) with high affinity. PACAP is involved in stimulating the secretion of insulin, catecholamines, ACTH, and growth hormone. Additionally, PACAP appears to function as a neuromodulator/neurotransmitter in the central and peripheral nervous systems. Two start codons are reported in literature, one (nt 74-76) results in a 525-amino acid protein with a signal peptide of 77 amino acids encoded by nt 74-304 and the second (nt 245-247) initiates a 468-amino acid protein with a signal peptide of 20-amino acids encoded by nt 245-304. The efficiency of these two start codons is not known.
Synonyms	ADCYAP1R1
Reference Data

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