Kir2.1 (KCNJ2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	ELISA. Western Blot: 1/50-1/200. Immunohistochemistry: 1/200-1/2000.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide derived from Nter domain of KCNJ2 protein
Specificity	Reacts with Human 48 kDa protein. Cross reacts with KCNJ2 from Mouse, Rat and several other species.
Formulation	0.1M Tris, 0.1M Glycine, 2% Sucrose State: Serum State: Lyophilized powder Preservative: None
Reconstitution Method	Restore in distilled water.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store prior to recosntitution at -20°C. Store reconstituted antibody at 2-8°C for one month or (in aliquots) at -20°C for longer.
Gene Name	potassium voltage-gated channel subfamily J member 2
Database Link	Entrez Gene 3759 Human UniProt ID P63252
Background	Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. This protein is an integral membrane protein and inward-rectifier type potassium channel. This protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is racterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features.
Synonyms	KCNJ2, HIRK1, Inward rectifier K(+) channel Kir2.1, Cardiac inward rectifier potassium channel, IRK1, Inward rectifier potassium channel 2
Reference Data

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