beta Arrestin 1 (ARRB1) pSer412 Rabbit Polyclonal Antibody

CAT#: AP55695PU-N

beta Arrestin 1 (ARRB1) pSer412 rabbit polyclonal antibody, Aff - Purified

Size: 50 ul 100 ul



Need it in bulk or conjugated?
Get a free quote

CNY 2,250.00


货期*
2周

规格
    • 100 ul

Product images

Specifications

Product Data
Applications IHC, WB
Recommend Dilution Western blot: 1:500~1:1000.
Immunohistochemistry on paraffin sections: 1:50~1:100.
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of Serine 412 (T-G-S(p)-P-Q) derived from Human Arrestin 1 (KLH-conjugated)
Specificity The antibody detects endogenous levels of Arrestin-1 only when phosphorylated at serine 412.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Condition Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Predicted Protein Size 50 kDa
Gene Name arrestin beta 1
Background Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation.
Synonyms ARR1, Beta-arrestin-1
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
Customer Reviews 
Loading...