DRP1 (DNM1L) pSer637 Rabbit Polyclonal Antibody

CAT#: AP55855PU-N

DRP1 (DNM1L) pSer637 rabbit polyclonal antibody, Aff - Purified



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CNY 2,250.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications WB
Recommend Dilution Western blot: 1:500~1:1000.
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of Serine637(K-L-S(p)-A-R) derived from Human DRP1 (KLH-conjugated)
Specificity The antibody detects endogenous levels of DRP1 only when phosphorylated at serine 637.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Affinity chromatography using epitope-specific peptide
Conjugation Unconjugated
Storage Condition Upon receipt, store undiluted (in aliquots) at -20°C.
Avoid repeated freezing and thawing.
Predicted Protein Size 82 kDa
Gene Name dynamin 1-like
Background Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation.
Synonyms DNM1L, DLP1, DRP1, Dynamin-like protein, Dnm1p/Vps1p-like protein, HdynIV
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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