CD57 / HNK1 Mouse Monoclonal Antibody [Clone ID: VC1.1]

Specifications

Product Data
Clone Name	VC1.1
Applications	FC, IHC, WB
Recommend Dilution	Suitable for use in Flow Cytometry (1 µg/1x10e6 cells/test), Western blotting and Immunohistology on formalin fixed paraffin embedded tissue sections.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Cat unfixed cortical homogenate area 17
Specificity	Recognizes a (Mr 110 kDa) carbohydrate molecule on Myeloid cells, known as CD57. This antibody blocks binding of HNK-1 (Leu. 7) antibody.(3)
Formulation	0.01 M PBS, pH 7.2 containing 1% BSA as stabilizer and 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified Ig fraction.
Concentration	lot specific
Purification	Protein A chromatography.
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for up to one month or in aliquots at -20°C long term. Avoid repeted freezing and thawing.
Background	The CD57 surface antigen is associated with myelin-associated glycoprotein (MAG).(1). The antigen is present on 15-20% of normal peripheral blood mononuclear cells. It is expressed on a subset of natural killer cells (60%) and on a subset of T-Lymphocytes. This carbohydrate is also present on N-CAM in the nervous system.
Synonyms	HNK-1, LEU7, NK-1, NK-Cell marker, NK1
Reference Data

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