CD24 Mouse Monoclonal Antibody [Clone ID: ALB9]
CAT#: BM2357
CD24 mouse monoclonal antibody, clone ALB9, Azide Free
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CNY 10,669.00
货期*
5周
规格
Cited in 1 publication. |
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Specifications
Product Data | |
Clone Name | ALB9 |
Applications | FC, IHC |
Recommend Dilution | Flow Cytometry: 2 µg/5x10e5cells/test. Immunohistochemistry on frozen sections or cell smears (1:25-1:50 dilution). Studies of peripheral blood B cells. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Human bone marrow malignant cells from a non-B, non-T acute leukemia |
Specificity | This antibody recongnizes CD24. The molecular weight of the recognized antigen is 35-45 kDa. Recognizes B cells from pre-B to mature-B stage. The ALB9 monoclonal antibody has been assigned to the CD24 cluster of differentiation at the sixth International Workshop on Human Leucocyte Differentiation Antigens held in Kobe, Japan in 1996. |
Formulation | PBS containing 1 mg/ml BSA as stabilizer, containing no preservatives State: Azide Free State: Lyophilized purified Ig fraction |
Reconstitution Method | Restore with 1 ml of distilled water. |
Concentration | lot specific |
Conjugation | Unconjugated |
Storage Condition | Store the reconstituted antibody at 2-8°C for one month (add 0.09% Sodium Azide) or at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | CD24 molecule |
Database Link | |
Background | CD24 (also known as heat stable antigen) is a phosphatidylinositol linked cell surface glycoprotein with a polypeptide core of 30 amino acids and high carbohydrate content. The apparent molecular mass of the two forms of CD24 purified from a mouse lymphoma cell line appear to be in the range of 40-60 and 23-30 kDa. CD24 is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+ CD8+ CD24+ thymocytes to either CD4+ CD8- CD24- or CD4- CD8+ CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. CD24 is also a positive marker of pancreatic cancer. |
Synonyms | X62 heat stable antigen, HSA |
Reference Data |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
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CD24 aggravates acute liver injury in autoimmune hepatitis by promoting IFN-γ production by CD4 + T cells
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Cellular and Molecular Immunology
,PubMed ID 28065940
[CD24]
|
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