ICAM1 Mouse Monoclonal Antibody [Clone ID: MEM-111]
CAT#: BM2448PE
ICAM1 mouse monoclonal antibody, clone MEM-111, PE
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CNY 4,340.00
货期*
5周
规格
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Specifications
Product Data | |
Clone Name | MEM-111 |
Applications | FC |
Recommend Dilution | Flow cytometry: 20 µl reagent / 100 µl of whole blood or 10e6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests. |
Reactivity | Bovine, Human, Rat |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Raji human Burkitt's lymphoma cell line |
Specificity | The antibody MEM-111 reacts with CD54 (ICAM-1), a 85-110 kDa type I transmembrane glycoprotein (receptor for rhinovirus). The expression of CD54 is upregulated by activation; it is expressed on activated endothelial cells, T lymphocytes, B lymphocytes, monocytes, macrophages, granulocytes and dendritic cells. |
Formulation | Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent Label: PE State: Liquid Ig fraction Label: Conjugated with R-Phycoerythrin under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use |
Conjugation | PE |
Storage Condition | Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. |
Gene Name | intercellular adhesion molecule 1 |
Database Link | |
Background | CD54 (ICAM-1) is a 90 kD member of the C2 subset of immunoglobulin superfamily. It is a transmembrane molecule with 7 potential N-glycosylated sites, expressed on resting monocytes and endothelial cells and can be upregulated on many other cells, e.g. with lymphokines, on B- and T-lymphocytes, thymocytes, dendritic cells and also on keratinocytes, chondrocytes, as well as epithelial cells. CD54 mediates cell adhesion by binding to integrins CD11a/CD18 (LFA-1) and to CD11b/CD18 (Mac-1). The interaction of CD54 with LFA-1 enhances antigen-specific T-cell activation. |
Synonyms | ICAM-1 |
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