RHCE (+ CD240D) Mouse Monoclonal Antibody [Clone ID: BRIC69]

Specifications

Product Data
Clone Name	BRIC69
Applications	ELISA, FC, IHC, IP
Recommend Dilution	Flow cytometry. Immunoprecipitation.
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Human erythrocytes.
Specificity	This antibody recognises erythrocytes of normal Rh types but does not recognise Rhnull erythrocytes. This antibody reacts with 31kD and 35-52kD proteins which were designated CD240DCE at the 7th leucocyte typing workshop.
Formulation	Tris buffered glycine, pH7.7 containing 0.09% Sodium Azide State: Purified State: Liquid purified IgG
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	Rh blood group CcEe antigens
Database Link	Entrez Gene 6006 Human UniProt ID P18577
Background	The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. There are thirteen named isoforms.
Synonyms	Rhesus C/E antigens, Rh30A, RhIXB, Rh polypeptide 1
Reference Data

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